Dr. Marco Antonio Juárez Oropeza

Study of cholesterol metabolism in different experimental models

OBJECTIVES

• To become acquainted with the factors regulating cholesterol synthesis, absorption and transformation and its interrelation with other lipids.

SUMMARY

Substances are studied that interfere with cholesterol synthesis and absorption. Diosgenin and the alga, Spirulina maxima, are evaluated in this group of substances. S. maxima also affects the hepatic synthesis of triacylglyceroles and phospholipids. In cholesterol transformation, steroid production by the gonads in different stages of development is studied.

PARTICIPANTS

• Patricia Torres Durán, B.Sc.
• Juan C. Díaz Zagoya, M.Sc.
• Dr. Enrique Pedernera Astegiano
• Dr. Pedro Nicolás Velázquez
• Yolanda de las Mercedes Gómez y Gómez, M.Sc.
• Cristina Paredes Carbajal, M.Sc.

BIBLIOGRAPHY

• 1. Cuevas Covarrubias S A, Miranda Zamora R, Juárez Oropeza M A, and Díaz Zagoya J C. (1994) Los ácidos grasos eritrocíticos de niños con desnutrición energético proteica grave. Rev. Invest. Clin. 46: 197-201.
• 2. Alvarez-Fernández G, Juárez -Oropeza M A, Velázquez P, González del Pliego M, Méndez- Herrera M C and Pedernera E. (1995) Newly hatched chick ovarian cell subpopulations metabolize distinctively progestin and androgen precursors. Gen. Comp. Endocrinol. 97:31-41.
• 3. Juárez-Oropeza M A, López V, Alvarez-Fernández G, Gómez Y and Pedernera E. (1995) Androstenedione metabolism in the indifferent stage of bovine gonad development. J. Exp. Zool. 271: 373-378.
• 4. Paredes-Carbajal M C, Juárez-Oropeza M A, Ortiz-Mendoza C M and Mascher D. (1995) Effects of acute and chronic estrogenic treatment on vasomotor responses of aortic rings from ovariectomized rats. Life Sciences. 57: 473-486.
• 5. Rodríguez-Maldonado E, Velázquez P N, Juárez-Oropeza M A and Pedernera E. Steroid metabolism in theca externa cells from preovulatory follicles of domestic hen (Gallus domesticus). Gen. Comp. Endocrinol. (en prensa).